CTGF is necessary for glucose tolerance during pregnancy, but overall β-cell mass is unchanged at the measured time-point.
Characterization of Novel Drugs that Target the Hedgehog Signaling Pathway in Tumor Induced Bone Disease
This research presents information about optimized transfection conditions for MDA-MB- 231 cells, as well as cell viability data on known antagonists.
A protocol for communication among a swarm of endoscopic submarine capsules was developed using light emitting diodes and color sensors.
This research aims to help children with autism develop their social skills.
Cave microorganisms were exposed to a variety of stimuli for the purpose of secondary metabolic pathway activation and potential acceleration of techniques for drug discovery.
Analyzing Specific Health Hazards in Perfumes by Identifying Ingredients using Gas Chromatography- Mass Spectrometry
The ingredients in perfumes were identified using Gas Chromatography-Mass Spectrometry then analyzed for health hazards based on data provided on publically available Safety Data Sheets as well as standards set by the United Nations Globally Harmonized System of Classification and Labelling of Chemicals.
Here the development of a novel microfluidic device is described that enhanced media perfusion that can benefit neurons cultured in a three-dimensional matrix, attempting to model the in vivo microenvironment in the brain.
The Effect of Trastuzumab, Paclitaxel, and XL147 Treatment on Aerobic Glycolysis in Breast Cancer Cells
This study evaluated the impact of select cancer treatments on the metabolic glucose consumption and lactate production of breast cancer cells.
Cell Shape Changes During Drosophila Germ Band Retraction: To-wards Model Validation by Experimental Comparison
This project seeks to experimentally validate simulated predictions of forces in a Drosophila embryo during germ band retraction.
Investigation of the Structure-Activity Relationship of a Dopamine Receptor 4 Antagonist to Treat Cocaine Addiction
This study demonstrates the successful synthesis of drug candidates for potential use as PET tracers and in vivo tool compounds to study and potentially treat cocaine addiction.
Evaluation of Bigby Cannon Limestone’s Contributions to Pedogenesis Using Element Mass Flux Calculations
Bigby Cannon Limestone was analyzed to see if it contributes to soil development in Middle Tennessee.
Experimental validation of theoretical results from a previously proposed traveling wave ion mobility model.
Development of a Two-Photon Lithography System
Carbon and Oxygen Isotope Analysis to Document Childhood Diet and Local vs. Non-Local Status among African Slave Burials from the Grassmere Plantation, Nashville, Tennessee
Carbon and oxygen isotope analyses of human teeth from a captive slave population from the Grassmere Plantation in Nashville, Tennessee.
This research looked at how Batrachochytrium dendrobatidis, a fungal pathogen that infects amphibians, is able to suppress immune function.
A Hybrid Photometric and Spectral Algorithm for Efficient Detection of Gravitationally Lensed Quasars
A novel method was developed to identify gravitationally lensed quasars, consisting of a morphological algorithm directed at finding wide-separation lens candidates and a point spread function (PSF)-difference-based algorithm aimed at identifying close-separation lens candidates.
This work uncovers that the function of RIF1 in DNA Double-Strand Break repair is likely mediated through the Single-Strand Annealing form of Homology-Directed Repair