May 2017 Issue
Analyzing Phospho-signaling in Human Glioblastoma Cell Lines Using Ex Vivo Culture
Phospho-protein activation was highest at the edges of organoids grown from glioblastoma cell lines, which may indicate key locations for potential treatment targets.
Posted by on Thursday, May 25th, 2017 in May 2017, cancer, Epidermal Growth Factor Receptor (EGFR), Glioblastoma, Organoid, phospho-protein activation
Analysis of Danger Posed by Near-Earth Asteroid 1994 PN
Analyze the orbit of asteroid 1994 PN to predict its potential of colliding with earth.
Posted by on Wednesday, May 24th, 2017 in May 2017, Asteroid, astrophysics, orbit determination
Development of Withdrawal Algorithm for Capsule Endoscopy in Research and Clinical Setting
An algorithm was developed to autonomously control the capsule endoscope, allowing doctor to focus on diagnosing the patient.
Posted by on Wednesday, May 24th, 2017 in May 2017, Endoscopy, external magnet, nanotechnology, python, simulation
POPDC3 Regulates Epithelial-Mesenchymal-Transition in Colorectal Cancer Cells
The POPDC3 protein was identified as a potential regulator of the epithelial-mesenchymal-transition process in colorectal cancer.
Posted by on Wednesday, May 24th, 2017 in May 2017, colorectal cancer, epithelial-mesenchymal transition, Popdc3
The Role of Aurora Kinase A (AURKA) in Regulating Translation of Oncogenes in Gastrointestinal Cancers
Aurora kinase A (AURKA) is frequently amplified and overexpressed in gastrointestinal cancers. In this report, we show that AURKA and EIF4E regulate the expression of the same oncogenes, suggesting that AURKA could play a role in regulating EIF4E-cap dependent translation of oncogenes. Inhibition of AURKA could be a plausible therapeutic approach in these cancers.
Posted by on Tuesday, May 16th, 2017 in May 2017, Gastrointestinal cancers, inhibition of AURKA, oncogenes, translation