May 2017 Issue
Phospho-protein activation was highest at the edges of organoids grown from glioblastoma cell lines, which may indicate key locations for potential treatment targets.
An algorithm was developed to autonomously control the capsule endoscope, allowing doctor to focus on diagnosing the patient.
The POPDC3 protein was identified as a potential regulator of the epithelial-mesenchymal-transition process in colorectal cancer.
The Role of Aurora Kinase A (AURKA) in Regulating Translation of Oncogenes in Gastrointestinal Cancers
Aurora kinase A (AURKA) is frequently amplified and overexpressed in gastrointestinal cancers. In this report, we show that AURKA and EIF4E regulate the expression of the same oncogenes, suggesting that AURKA could play a role in regulating EIF4E-cap dependent translation of oncogenes. Inhibition of AURKA could be a plausible therapeutic approach in these cancers.